XIE LAB PUBLICATIONS

9. M. Xie and J. Bungert, When Pol II sees red. Blood, in press (2021)

8. D. Stribling*, Y. Lei*, C.M. Guardia*, L. Li, C.J. Fields, P. Nowialis, R. Opavsky, R. Renne# and M. Xie#, A non-canonical microRNA derived from the snaR-A non-coding RNA targets a metastasis inhibitor. RNA, in press (2021).

7. A. Gurumurthy, D. Yu, J.R. Stees, P. Chamales, E. Gavrilova, P. Wassel, L. Li, D. Stribling, J. Chen,  M. Brackett, A. Ishov, M. Xie and J. Bungert, Super-enhancer mediated regulation of adult β-globin gene expression: the role of eRNA and Integrator. Nucleic Acids Research, 49, 1383-1396 (2021).

6. M. Xie and M.S. Swanson, UTteR control through miRs: fine-tuning ATXN1 levels to prevent ataxia. Genes & Development, 34, 1107-1109 (2020).

5. P. Sheng, K.A. Flood and M. Xie, Short hairpin RNAs for strand-specific small interfering RNA production. Frontiers in Bioengineering & Biotechnology, 8, 940  (2020).

4. P. Nowialis*, K. Lopusna*, J. Opavska, S.L. Haney, A. Abraham, P. Sheng, A. Riva, A. Natarajan, O. Guryanova, M.Simpson, R. Hlady, M. Xie and R. Opavsky, Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions. Nature Communications, 10, 4374 (2019).

3. C.J. Fields, P. Sheng, B.R. Miller, T. Wei and M. Xie, Northern blot with IR fluorescent probes: Strategies for probe preparation. Bio-protocol, 9: e3219 (2019).

2. B.R. Miller*, T. Wei*, C.J. Fields, P. Sheng and M. Xie, Near-infrared fluorescent northern blot. RNA, 24, 1871-1877 (2018).

1. P. ShengC.J. Fields, K. Aadland, T. Wei, O. Kolaczkowski, T. Gu, B. Kolaczkowski# and M. Xie#Dicer cleaves 5′-extended microRNA precursors originating from RNA Polymerase II transcription start sites. Nucleic Acids Research46, 5737-5752 (2018).

(lab members highlighted in bold)

Ming’s Postdoc Work

9. K.E. Hayes, J.A. Barr, M. Xie, J.A. Steitz and I. Martinez, Immunoprecipitation of Tri-methylated Capped RNA. Bio-protocol, 8 : e2717 (2018).

8. I. Martinez, K. Hayes, J. Barr, A. Harold, M. Xie, S.I.A. Bukhari, S. Vasudevan, J.A. Steitz and D. DiMaio, An Exportin-1-dependent microRNA biogenesis pathway during human cell quiescence. Proc. Natl. Acad. Sci. U.S.A. 114, 4961-4970 (2017).

7. W. Zhang*, M. Xie*, M. Shu, J.A. Steitz and D. DiMaio, A proximity-dependent assay for specific RNA-protein interactions in intact cells. RNA, 22, 1785-1792 (2016).

6. M. Xie, W. Zhang, M. Shu, A. Xu, D. Lenis, D. DiMaio and J.A. Steitz, The host Integrator complex acts in transcription-independent maturation of herpesvirus microRNA 3′ ends. Genes & Development, 29, 1552-1564 (2015).

5. K.T. Tycowski*, Y.E. Guo*, N. Lee*, W.N. Moss*, T.K. Vallery*, M. Xie* and J.A. Steitz, Viral noncoding RNAs: more surprises. Genes & Development, 29, 567-584 (2015).

4. M. Xie# and J.A. Steitz, Versatile microRNA biogenesis in animals and their viruses. RNA biology,11, 673-681 (2014).

3. M. Xie, M. Li, A.Vilborg, N. Lee, M. Shu, V. Yartseva, N. Sestan and J.A. Steitz, Mammalian 5′-capped microRNA precursors that generate a single microRNA. Cell, 155, 1568-1580 (2013).

2. C. Qiao, J. Ma, J. Xu, M. Xie, W. Ma and Y. Huang, Drosha mediates destabilization of Lin28 mRNA targets. Cell Cycle, 11, 3590-3598 (2012).

1. D. Cazalla, M. Xie and J.A. Steitz, A primate Herpesvirus uses the Integrator complex to generate viral microRNAs. Molecular Cell, 43, 982-992 (2011).

MING’S GRADUATE WORK

8. A.F. Brown, J.D. Podlevsky, X. Qi, Y. Chen, M. Xie and J.J.-L. Chen, A self-regulating template in human telomerase. Proc. Natl. Acad. Sci. U.S.A. 111, 11311-11316 (2014).

7.   X. Qi*, M. Xie*,  A.F. Brown*, C.J. Bley, J.D. Podlevsky and J.J.-L. Chen, RNA/DNA hybrid binding affinity determines telomerase template translocation efficiency. EMBO Journal, 31, 150-161 (2012).

6. M. Xie, J.D. Podlevsky, X. Qi, C.J. Bley and J.J.-L. Chen, A novel motif in telomerase reverse transcriptase regulates telomere repeat addition rate and processivity. Nucleic Acids Research, 38, 1982-1996 (2010).

5. M. Xie, A. Mosig, X. Qi, Y. Li, P.F. Stadler and J.J.-L. Chen, Structure and function of the smallest vertebrate telomerase RNA from teleost fish. Journal of Biological Chemistry, 283, 2049-2059 (2008).

4. J.K. Alder, J.J.-L. Chen, L. Lancaster, S. Danoff, S.C. Su, M. Prince, I. Vulto, M. Xie, X. Qi, R.M. Tuder, J.A. Phillips, P.M. Lansdorp, J.E. Loyd, and M.Y. Armanios, Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proc. Natl. Acad. Sci. U.S.A.105, 13051-13056 (2008).

3. Y. Xiang, M. Xie, R. Bash, J.J.-L. Chen, and J. Wang, Ultrasensitive label-free aptamer-based electronic detection. Angew. Chem. Int. Ed., 46, 9054-9056(2007).

2. M. Armanios, J.J.-L. Chen, W.E. Lawson, J.K. Alder, R.G. Ingersoll, C. Markin, M. Xie, J. Cogan, J.A. Philips III, P.M. Lansdorp, C.W. Greider and J.E. Loyd, Telomerase mutations in families with idiopathic pulmonary fibrosis.  New England Journal of Medicine,356, 1317-1326 (2007).

1.  C. Lin, M. Xie, J.J.-L. Chen, Y. Liu, and H. Yan, Rolling-circle amplification of a DNA nanojunction. Angew. Chem. Int. Ed., 45, 7537-7539(2006).

MING’S UNDERGRADUATE WORK

3. X. Zhu, Z. Li, M. Xie, A. Song, and Y. Liu. [Effect of illumination through simulated forest gap on the germination of seed bank in Hexi subtropical rainforest in Nanjing, China. in Chinese] Journal of Xiamen University (Natural Sci.), 45,125-130 (2006).

2. J. Zheng, Y. Gao, Q. Wei, J. Ouyang, C. Tang and M. Xie, Optimization of cultivation technique for Ca-enriched Spirulina maxima. Journal of Jimei University (Natural Sci.), 9, 205-209(2004).

1. J. Zheng, Y. Gao, Q. Wei, J. Ouyang, C. Tang and M. Xie, [Distribution of calcium and changes of the major biochemical components in Spiraling maxima after the addition of CaCO3. in Chinese] Chinese Fishery Sciences, 11, 462-466(2004).

(* equal contribution, # corresponding author)